79317-98-9Relevant academic research and scientific papers
4-Trimethylsilyl-5-iodo-1,2,3-triazole: A key precursor for the divergent syntheses of 1,5-disubstituted 1,2,3-triazoles
Li, Lingjun,Shang, Tongpeng,Ma, Xiaonan,Guo, Haiyun,Zhu, Anlian,Zhang, Guisheng
, p. 695 - 699 (2015)
Bifunctional 4-trimethylsilyl-5-iodo-1,2,3-triazoles (TMSIT) were reported in this paper, which could be efficiently synthesized directly from readily accessible TMS-alkyne, azide, and copper(I) iodide at room temperature. Using TMSIT as key precursors, a divergent protocol for the preparation of 1,5-disubstituted 1,2,3-triazoles was developed via sequential copper/palladium-catalyzed coupling reactions and desilylation in one pot.
Reaction of diacetylenic compounds with benzyl azide
Tikhonova, L. G.,Serebryakova, E. S.,Proidakov, A. G.,Sokolova, I. E.,Vereshchagin, L. I.
, p. 645 - 648 (2007/10/02)
Substituted mono- and di-1,2,3-triazoles were obtained by the reaction of conjugated diacetylenic compounds with benzyl azide.It was shown that the addition of the first mole of the azide takes place exclusively at the terminal triple bond.
