79325-33-0 Usage
General Description
3,4-dichloro-2-(trichloromethyl)quinoline is a chemical compound with the molecular formula C10H5Cl5N. It is a quinoline derivative with two chloro substituents at the 3 and 4 positions and a trichloromethyl group attached to the 2 position of the quinoline ring. 3,4-dichloro-2-(trichloromethyl)quinoline is a white solid that is sparingly soluble in water but is soluble in organic solvents. It is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals due to its unique chemical structure and reactivity. Additionally, it has also been used in research as a building block for the preparation of novel organic compounds. In terms of its hazards, 3,4-dichloro-2-(trichloromethyl)quinoline is considered to be a skin and eye irritant and should be handled with proper precautions in a controlled laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 79325-33-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,3,2 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 79325-33:
(7*7)+(6*9)+(5*3)+(4*2)+(3*5)+(2*3)+(1*3)=150
150 % 10 = 0
So 79325-33-0 is a valid CAS Registry Number.
79325-33-0Relevant articles and documents
Trichloromethylquinolines: Synthesis and Reaction with Trimethyl Phosphite
Kato, Tetsuzo,Katagiri, Nobuya,Wagai, Akihiro
, p. 1069 - 1075 (2007/10/02)
Heating of methylquinolines (1, 3, 6, and 12) with phosphorus pentachloride in phosphoryl chloride gave the corresponding trichloromethylquinoline derivatives (2, 4, 9, and 14).Similar treatment of 4-chloro-2-methyl-3-nitroquinoline (16) gave 4-chloro-2-dichloromethyl-3-nitroquinoline (17), 4-chloro-3-nitro-2-trichloromethylquinoline (18), and 3,4-dichloro-2-cyanoquinoline (19).The reaction of 2-trichloromethylquinolines (2, 9, and 18) with trimethyl phosphite gave the corresponding methylated products, 2-(1,1-dichloroethyl)quinolines (21, 24, and 27).However, 4-trichloromethylquinolines (4 and 14) reacted with trimethyl phosphite under similar conditions to give 4-dichloromethylquinolines (23 and 13).Keywords - chlorination; dichloromethylquinolines; trichloromethylquinolines; phosphorus pentachloride, phosphoryl chloride, trimethyl phosphite; methylation; phosphorylation; 2-(1,1-dichloroethyl)quinolines.
