793675-33-9

Usage

Uses

Used in Organic Synthesis:
(2-chloropyridin-3-yl)cyclohexylamine is used as a building block in organic synthesis for the creation of various chemical compounds. Its unique structure allows for the formation of new molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
(2-chloropyridin-3-yl)cyclohexylamine is used as a potential pharmaceutical compound for the development of new drugs. Its specific structure may contribute to the discovery of novel therapeutic agents with improved efficacy and safety profiles.
Used in Chemical Research:
(2-chloropyridin-3-yl)cyclohexylamine is used as a research compound in the field of chemistry. Its unique properties and potential applications make it a valuable tool for studying chemical reactions and exploring new areas of chemical science.

Upstream product

• 78607-36-0 2-chloro-3-iodopyridine 
• 108-91-8 cyclohexylamine 
• 154377-28-3 (2-Chloro-pyridin-3-yl)-cyclohexylidene-amine 
• 6298-19-7 2-chloro-3-aminopyridine 
• 108-94-1 cyclohexanone 
• 1670-47-9 1,1-diethoxycyclohexane 

Downstream Products

• 1365094-43-4 1-cyclohexyl-1H-imidazo[4,5-b]pyridine 
• 864365-02-6 dithiocarbonic acid S-{[(2-chloro-pyridin-3-yl)-cyclohexyl-carbamoyl]-methyl} ester O-ethyl ester 
• 906532-75-0 1-(2-chloro-pyridin-3-yl)-1-cyclohexylurea 
• 793675-34-0 N³-cyclohexyl-N²-(4-{[4-(methylsulfonyl)piperazin-1-yl]methyl}phenyl)pyridine-2,3-diamine 

Relevant academic research and scientific papers

Synthesis of imidazo[4,5-b]pyridines and imidazo[4,5-b]pyrazines by palladium catalyzed amidation of 2-chloro-3-amino-heterocycles

A facile synthesis of imidazo[4,5-b]pyridines and-pyrazines is described using a Pd-catalyzed amide coupling reaction. This reaction provides quick access to products with substitution at N1 and C2. A model system relevant to the natural product pentosidi

Efficient access to azaindoles and indoles

An expedient, catalytic method for the synthesis of diverse azaindoles and indoles, starting from readily available and inexpensive starting materials, is described. Conditions were developed for effective reductive alkylation of electron-deficient o-chlo

Efficient access to cyclic ureas via Pd-catalyzed cyclization

An efficient regioselective method for the preparation of structurally diverse imidazopyridinones and benzoimidazolones starting from readily available and economical starting materials is described. High-yielding reductive alkylation of electron-deficient o-haloarylamines followed by treatment with inexpensive N-chlorosulfonyl isocyanate afforded primary ureas in good overall yields. A Pd-catalyzed urea cyclization reaction furnished imidazopyridinones and benzoimidazolones in excellent yields. Overall, the developed chemistry provides rapid access to pharmaceutically important heterocyclic compounds with high efficiency.

An unusual radical smiles rearrangement

(Chemical Equation Presented) Radicals derived from N-(α-xanthyl) acetanilides or N-(α-xanthyl)acetylaminopyridines possessing a substituent next to the nitrogen undergo a hitherto undocumented Smiles rearrangement proceeding through a four-membered ring.

Synthesis of disubstituted imidazo[4,5-b]pyridin-2-ones

Regioselective palladium-catalyzed amination of 2-chloro-3-iodopyridine followed by a subsequent palladium-catalyzed amination leads to 2,3-diaminopyridines. Treatment with triphosgene affords highly functionalized unsymmetrical imidazo [4,5-b] pyridin-2-