793684-17-0

Upstream product

• 43179-41-5 O,O-(5S,6S)-trans-(-)-5-bromo-6-hydroxy-5,6-dihydrothymidine-3',5'-diyldiacetate 
• 6979-97-1 3',5'-diacetylthymidine 
• 108-98-5 thiophenol 
• 793684-09-0 Acetic acid (2R,3S,5R)-2-acetoxymethyl-5-((5S,6R)-5-hydroxy-5-methyl-2,4-dioxo-6-phenylsulfanyl-tetrahydro-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 

Downstream Products

• 793684-26-1 Phosphoric acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl ester (2R,3S,5R)-3-hydroxy-5-((5S,6R)-5-hydroxy-5-methyl-2,4-dioxo-6-phenylsulfanyl-tetrahydro-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 

Relevant academic research and scientific papers

Independent generation of the 5-hydroxy-5,6-dihydrothymidin-6-yl radical and its reactivity in dinucleoside monophosphates

Hydroxyl radical is a major reactive oxygen species produced by γ-radiolysis of water or Fenton reaction. It attacks pyrimidine bases and gives the 5-hydroxy-5,6-dihydropyrimidin-6-yl radical as the major product. Here we report the synthesis of all four