793685-05-9

Upstream product

• 793685-03-7 (5R,6S,6aS)-5-(tert-Butyl-dimethyl-silanyloxy)-6-((Z)-(R)-5-methoxy-hept-2-enyl)-3-trimethylsilanyl-4,5,6,6a-tetrahydro-1H-pentalen-2-one 
• 793684-99-8 6-(2-benzyloxy-ethyl)-5-(tert-butyl-dimethyl-silanyloxy)-3-trimethylsilanyl-4,5,6,6a-tetrahydro-1H-pentalen-2-one 
• 793685-00-4 5-(tert-butyl-dimethyl-silanyloxy)-6-(2-hydroxy-ethyl)-3-trimethylsilanyl-4,5,6,6a-tetrahydro-1H-pentalen-2-one 
• 793685-01-5 [(1S,2R,6aS)-2-(tert-Butyl-dimethyl-silanyloxy)-5-oxo-4-trimethylsilanyl-1,2,3,5,6,6a-hexahydro-pentalen-1-yl]-acetaldehyde 
• 1005-56-7 phenylcarbonochloridothioate 
• 793685-04-8 (3aR,4S,5R,6aS)-5-Hydroxy-4-((R)-5-methoxy-heptyl)-hexahydro-pentalen-2-one 

Downstream Products

• 89672-11-7 cyoctol 

Relevant academic research and scientific papers

Stereocontrolled synthesis of all eight stereoisomers of the putative anti-androgen cyoctol

All eight stereoisomers (1-4 and enantiomers) of the putative anti-androgen cyoctol have been synthesized along stereochemically unambiguous routes. The biological tests of all isomers indicated that cyoctol is not an anti-androgen, contrary to the patent literature. All eight stereoisomers of the putative anti-androgen cyoctol have been prepared and tested biologically.