793686-31-4

Upstream product

• 100-44-7 benzyl chloride 
• 15028-56-5 4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane 
• 13071-59-5 3-benzyloxypropan-1,2-diol 
• 105-38-4 vinyl propionate 
• 802294-64-0 propionic acid 
• 793686-32-5 Propionic acid (R)-3-benzyloxy-2-hydroxy-propyl ester 

Downstream Products

• 30403-51-1 1,2-di-O-hexacecanoyl-3-O-benzyl-sn-glycerol 
• 56552-80-8 (R)-3-benzyloxy-1,2-propanediol 
• 17325-85-8 (2S)-3-(benzyloxy)propane-1,2-diol 

Relevant academic research and scientific papers

Efficient chemoenzymatic enantioselective synthesis of diacylglycerols (DAG)

A new efficient chemoenzymatic methodology for the production of 3-O-benzyl-sn-glycerol and 1,2-O-dipalmitoyl-sn-glycerol has been developed. It starts from racemic 1-O-benzylglycerol and is based on the sequential enzymatic acylation-Mitsunobu inversion-enzymatic hydrolysis, which has been performed without isolation of the intermediates. In this way a 70-75% yield of 3-O-benzyl-sn-glycerol with 94-96% ee has been obtained.