79379-57-0Relevant academic research and scientific papers
Microwave-assisted zinc chloride-catalyzed synthesis of substituted pyrroles from homopropargyl azides
Wyrebek, Przemys?aw,Sniady, Adam,Bewick, Nicholas,Li, Yan,Mikus, Agnieszka,Wheeler, Kraig A.,Dembinski, Roman
experimental part, p. 1268 - 1275 (2009/04/10)
Ligand-free 5-endo-dig cyclization of 1,4- and 1,2,4-substituted but-3-yn-1-yl (homopropargyl) azides in the presence of zinc chloride (usually 20 mol %) in dichloroethane at elevated temperature provides 2,5-di- and 2,3,5-trisubstituted pyrroles in high
Synthesis of Pyrrole Derivatives from 5,6-Dihydro-4H-1,2-oxazines via Reductive Deoxygenation by Use of Fe3(CO)12
Nakanishi, Saburo,Otsuji, Yoshio,Itoh, Keiji,Hayashi, Nobuaki
, p. 3595 - 3600 (2007/10/02)
α-Bromooximes such as α-bromoacetophenone oxime and ethyl 3-bromo-2-(hydroxyimino)propanoate react with enamines to give 5,6-dihydro-4H-1,2-oxazines in good yields.Dihydro-1,2-oxazine derivatives are also obtained by the reaction of α-bromooximes with vinyl ethers and silyl enol ethers in the presence of Na2CO3.Dihydro-1,2-oxazines can be converted into pyrrole derivatives via reductive deoxygenation by treating with Fe3(CO)12 in moderate to excellent yields.Iron carbonyl complexes other than Fe3(CO)12 are also effective for the pyrrole-forming reaction.The efficiency of the complexes for this reaction decreases in the or der: Fe3(CO)12 >> Et3NH > Fe2(CO)9 >> Fe(CO)5.Both of the dihydro-1,2-oxazine- and pyrrole-forming reactions can be carried out in a single flask, giving pyrrole derivatives in good yields.
Regioselective Photo-oxygenation of 2-Aryl-4,5,6,7-tetrahydroindoles: Preparation and Reactions of 2-Aryl-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenines
Mizuno, Kazuhiko,Ohmura, Nobuhiko,Nakanishi, Saburo,Otsuji, Yoshio
, p. 355 - 356 (2007/10/02)
Dye-sensitized photo-oxygenation of 2-aryl-4,5,6,7-tetrahydroindoles quantitatively afforded 2-aryl-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenines, which were converted into the corresponding hydroxy-indolenines and spiro-γ-lactams in excellent yields.
