79405-51-9

Basic information

• Product Name: Ethyl 2,3 - dibroMo - 3 - Methylbutanoate
• Synonyms: Ethyl 2,3 - dibroMo - 3 - Methylbutanoate
• CAS NO: 79405-51-9
• Molecular Formula: C₇H₁₂Br₂O₂
• Molecular Weight: 287.97698
• Mol File: 79405-51-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Ethyl 2,3 - dibroMo - 3 - Methylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2,3 - dibroMo - 3 - Methylbutanoate(79405-51-9)
• EPA Substance Registry System: Ethyl 2,3 - dibroMo - 3 - Methylbutanoate(79405-51-9)

Safety Data

• Hazardous Substances Data: 79405-51-9(Hazardous Substances Data)

Upstream product

• 638-10-8 ethyl 3-methylbut-2-enoate 

Downstream Products

• 84024-59-9 ethyl 3,3-dimethylaziridin-2-carboxylate 
• 584-27-0 2-isopropylidenesuccinic acid 

Relevant articles and documents

A Metal-Free Domino Process for Regioselective Synthesis of 1,2,4-Trisubstituted Pyrroles: Application toward the Formal Synthesis of Ningalin B

A new one-pot, transition-metal, acid/base-free domino process is developed for the regioselective synthesis of 1,2,4-trisubstituted pyrroles. The process involves 1,3-dipolar cycloaddition of unsymmetrical azomethine ylide resulting from the thermal C-C bond cleavage of unactivated aziridines with β-bromo-β-nitrostyrene, followed by a cascade of elimination and aromatization reaction sequence to preferentially furnish 1,2,4-trisubstituted pyrroles instead of the expected 1,2,3-trisubstituted pyrroles, in good to excellent yields. Further, the application of the methodology for the formal synthesis of ningalin B is delineated.

A facile route to a versatile synthon for preparation of cis-pyrethroids

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