79420-24-9Relevant articles and documents
Phenylimidazole derivatives as new inhibitors of bacterial enoyl-ACP reductase FabK
Kitagawa, Hideo,Ozawa, Tomohiro,Takahata, Sho,Iida, Maiko
, p. 4982 - 4986 (2008/03/13)
Novel FabK inhibitors with antibacterial activity against Streptococcus pneumoniae were synthesized and evaluated. Through SAR studies of our initial hit compound 2-(1H-benz[d]imidazol-2-ylthio)-N-(6-methoxycarbonylbenzo[d]thiazol-2-yl)acetamide, a series of novel phenylimidazole derivatives were discovered as potent FabK inhibitors.
Synthesis and biological activities of some new 2-(N-heterocyclic carboxamidomethyl thio) benzoxazoles, benzthiazoles and benzimidazoles. Part VIII.
Mahmoud,El-Sherief,Abdel-Rahman
, p. 383 - 384 (2007/10/02)
-