794450-92-3Relevant articles and documents
Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4
Kaku, Teppei,Ogura, Kenichiro,Nishiyama, Takahito,Ohnuma, Tomokazu,Muro, Kei,Hiratsuka, Akira
, p. 2093 - 2102 (2004)
Tamoxifen (TAM), a nonsteroidal antiestrogen, is the most widely used drug for chemotherapy of hormone-dependent breast cancer in women. In the present study, we found a new potential metabolic pathway of TAM via N-linked glucuronic acid conjugation for e