794520-17-5

Upstream product

• 5927-18-4 trimethyl phosphonoacetate 
• 4255-62-3 4,4-dimethylcyclohexane-1-one 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 1210879-61-0 (4,4-dimethylcyclohexyl)acetic acid methyl ester 
• 105962-04-7 (1E)-2-(4',4'-dimethylcyclohex-1'-enyl)-N,N-dimethylethen-1-ylamine 

Relevant academic research and scientific papers

SUBSTITUTED AMINOTHIAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE

Substituted aminothiazole derivatives, methods of their preparation, pharmaceutical compositions comprising a substituted aminothiazole, and methods of use in treating human or animal disorders. The compounds may be useful as inhibitors of action of AgRP on a melanocortin receptor and thus may be useful for the management, treatment, control, or the adjunct treatment of diseases which may be responsive to the modulation of melanocortin receptors including obesity-related disorders.

98. A Regioselective Cyclohexannulation Procedure via Dienamine Cycloaddition. Synthesis of Functionalised Decalins

A regioselective cyclohexannulation procedure, whose key step involves the cycloaddition of dienamines 12-24 with methyl acrylate, allows the conversion of cycloalkanones 1-11 to bicyclic dienoates 25-37.The chemistry of 26 is briefly examined and, in the context of organoleptic studies concerning functionalised 5,5,9-trimethyldecalins, the transformation of 37 to ketones 44 and 46 as well as to acetates 53-56 is described.

DIENAMINES AS DIELS-ALDER DIENES. AN EFFICIENT CYCLOHEXANNULATION SEQUENCE.

An efficient cyclohexannulation sequence is described whose key step involves a Diels-Alder reaction between an (E)-dienamine and methyl acrylate.