794529-80-9

Upstream product

• 120095-64-9 2,2,2-trichloro-1-(1-methyl-4-nitro-1H-imidazol-2-yl)ethan-1-one 
• 633302-89-3 [(1-methyl-4-nitro-1H-imidazole-2-carbonyl)amino]acetic acid methyl ester 

Downstream Products

• 633302-92-8 5-benzyloxy-1-chloromethyl-7-{3-[2-(methoxycarbonylmethylcarbamoyl)-1-methyl-1H-imidazol-4-ylcarbamoyl]propionylamino}-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester 
• 633302-98-4 C₆₃H₆₇Cl₂N₉O₁₁ 
• 633303-01-2 C₆₀H₆₁Cl₂N₉O₁₀ 
• 633302-95-1 5-benzyloxy-7-{3-[2-(carboxymethylcarbamoyl)-1-methyl-1H-imidazol-4-ylcarbamoyl]propionylamino}-1-chloromethyl-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester 
• 861960-13-6 C₅₁H₇₂N₁₀O₁₄S₄ 
• 861960-07-8 ({4-[4-(4-{(2S)-2-[bis(ethylsulfanyl)methyl]pyrrolidine-1-carbonyl}-2-methoxy-5-nitrophenoxy)butyrylamino]-1-methyl-1H-imidazole-2-carbonyl}amino)acetic acid 
• 861960-01-2 ({4-[4-(4-{(2S)-2-[bis(ethylsulfanyl)methyl]pyrrolidine-1-carbonyl}-2-methoxy-5-nitrophenoxy)butyrylamino]-1-methyl-1H-imidazole-2-carbonyl}amino)acetic acid methyl ester 

Relevant academic research and scientific papers

Design, synthesis and in vitro cytotoxic studies of novel bis-pyrrolo[2,1][1,4] benzodiazepine-pyrrole and imidazole polyamide conjugates

The design, synthesis and biological evaluation of novel pyrrolo [2,1][1,4] benzodiazepine (PBD) dimers 38-43 linked with pyrrole and imidazole polyamides from either side by a flexible methylene chain of variable length are described, which involved merc

Synthesis and cytotoxicity evaluation of novel C7-c7, C7-N3 and N3-N3 dimers of 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benzo[e]indole (seco-CBI) with pyrrole and imidazole polyamide conjugates.

The C7-C7, C7-N3 and N3-N3 dimers of 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benzo[e]indole (seco-CBI) with pyrrole and imidazole polyamides were synthesized and preliminary anti-cancer evaluation carried out by NCI against three types of cancer cells.