79464-57-6

Upstream product

• 589-92-4 1-methylcyclohexan-4-one 
• 60164-94-5 (+)-(S)-(4-Methylcyclohexylidene)bromomethane 
• 74-88-4 methyl iodide 
• 91633-73-7 (3aR,7aR)-2-ethyl-<3a,4,5,6,7,7a-octahydro-1,3-dimethyl-1,3,2-benzodiazaphosphole>-2-oxide 
• 146397-35-5 1-{(S)-1-[(3aR,7aR)-1,3-Bis-(2,2-dimethyl-propyl)-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl]-ethyl}-4-methyl-cyclohexanol 

Downstream Products

• 146397-36-6 (2R,3R,4R)-1,2-Bis-benzyloxy-4-((S)-4-methyl-cyclohex-1-enyl)-pentan-3-ol 
• 146397-36-6 (2R,3R,4R)-1,2-Bis-benzyloxy-4-((R)-4-methyl-cyclohex-1-enyl)-pentan-3-ol 
• 146397-37-7 (2R,3R,4R)-4-((R)-4-Methyl-cyclohex-1-enyl)-pentane-1,2,3-triol 
• 146397-37-7 (2R,3R,4R)-4-((S)-4-Methyl-cyclohex-1-enyl)-pentane-1,2,3-triol 

Relevant academic research and scientific papers

Versatile synthesis of alicyclic and acyclic compounds with alternate and remote C-methyl substitution patterns via asymmetric sequential olefination and ene reactions

Treatment of enantiomerically pure alkyl cyclohexane ethylidene derivatives with 2,3-di-O-benzyl D- and L-glyceraldehyde and related aldehydes in the presence of Lewis acids leads to enantiomerically pure or enriched branched alkylcyclohexenes. These can

Stereochemistry of Transition-Metal-Catalyzed Cross-Coupling Reactions

The stereochemical results of transition-metal-catalyzed cross-coupling of methyllithium with chiral (+)-(S)-(4-methylcyclohexylidene)bromomethane (1) are reported.The use of bis(triphenylphosphine) dichlorocobalt(II), iron(III) tris(dibenzoylmethide), and dichloronickel(II) yielded chiral 1-methyl-4-ethylidenecyclohexane (2) with 89percent, 96percent, and 96percent retention of configuration, respectively.By contrast, the use of silver bromide yielded totally racemic product.