Ferritin is the cellular storage protein for iron, responsible for binding and storing most of the iron within the body. It is found in various tissues such as the liver, spleen, skeletal muscles, and bone marrow, with a small amount present in the blood. Ferritin's hollow core allows it to store a significant quantity of iron, acting as an essential storage system for iron within cells. Its primary role is to protect cells from damage caused by the Fenton reaction, which involves the production of harmful reactive oxygen species from free Fe(II) in oxidizing conditions.
79468-83-0
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Basic information
- Product Name: Ferritin
- Synonyms: FERRITIN;Ferritin (horse spleen protein moiety reduced)
- CAS NO:79468-83-0
- Molecular Formula:
- Molecular Weight: 0
- EINECS: 232-704-0
- Product Categories: proteins
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: Ferritin(CAS DataBase Reference)
- NIST Chemistry Reference: Ferritin(79468-83-0)
- EPA Substance Registry System: Ferritin(79468-83-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 79468-83-0(Hazardous Substances Data)
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79468-83-0 Usage
Uses
Used in Medical Diagnostics:Ferritin is used as a biomarker for assessing iron levels in the body. The serum ferritin concentration correlates well with total-body iron stores, making its measurement crucial in diagnosing disorders of iron metabolism. A ferritin level blood test can help identify conditions such as iron deficiency, anemia, excessive menstrual bleeding, stomach conditions affecting intestinal absorption, and internal bleeding.
Used in Monitoring Iron-Related Conditions:
Ferritin is used as an indicator to monitor various conditions related to iron levels. High ferritin levels can suggest the presence of certain conditions, including hemochromatosis, rheumatoid arthritis, liver disease, hyperthyroidism, adult Still's disease, type 2 diabetes, leukemia, Hodgkin's lymphoma, iron poisoning, and frequent blood transfusions. Regular monitoring of ferritin levels can help in the early detection and management of these conditions.
Hazard
Questionable carcinogen; neoplastigen; mutagen.References
[1] http://www.webmd.com [2] http://www.healthline.comCheck Digit Verification of cas no
The CAS Registry Mumber 79468-83-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,4,6 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.Calculate Digit Verification of CAS Registry Number 79468-83:
(7*7)+(6*9)+(5*4)+(4*6)+(3*8)+(2*8)+(1*3)=190
190 % 10 = 0
So 79468-83-0 is a valid CAS Registry Number.
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Ferritin
