79481-75-7Relevant academic research and scientific papers
A simple synthesis of photolabile α-methyl nitrobenzyl compounds
Salerno, Charles P.,Cleaves, Henderson J.
, p. 2379 - 2386 (2004)
α-Methyl nitrobenzyl compounds have demonstrated superior photochemical release properties when compared to nitrobenzyl compounds lacking α-methyl substitution at the benzylic position. The synthesis of 4-(1-hydroxy-ethyl)-3-nitro-benzoic acid ethyl ester
Synthetic, structural mimetics of the β-hairpin flap of HIV-1 protease inhibit enzyme function
Chauhan, Jay,Chen, Shen-En,Fenstermacher, Katherine J.,Naser-Tavakolian, Aurash,Reingewertz, Tali,Salmo, Rosene,Lee, Christian,Williams, Emori,Raje, Mithun,Sundberg, Eric,Destefano, Jeffrey J.,Freire, Ernesto,Fletcher, Steven
, p. 7095 - 7109 (2015/11/11)
Small-molecule mimetics of the β-hairpin flap of HIV-1 protease (HIV-1 PR) were designed based on a 1,4-benzodiazepine scaffold as a strategy to interfere with the flap-flap protein-protein interaction, which functions as a gated mechanism to control acce
High-yielding and photolabile approaches to the covalent attachment of biomolecules to surfaces via hydrazone chemistry
Lee, Ju Hun,Domaille, Dylan W.,Noh, Hyunwoo,Oh, Taeseok,Choi, Chulmin,Jin, Sungho,Cha, Jennifer N.
, p. 8452 - 8460 (2014/08/05)
The development of strategies to couple biomolecules covalently to surfaces is necessary for constructing sensing arrays for biological and biomedical applications. One attractive conjugation reaction is hydrazone formation - the reaction of a hydrazine w
