79510-59-1

Upstream product

• 123-54-6 acetylacetone 
• 51978-97-3 3-methyl-4-nitro-5-(4-chlorostyryl)isoxazole 
• 104-88-1 4-chlorobenzaldehyde 
• 1123-49-5 3,5-dimethyl-4-nitroisoxazole 

Downstream Products

• 78636-38-1 5-[2-(3,5-dimethylisoxazol-5-yl)-2-(4-chlorophenyl)ethyl]-3-methyl-4-nitroisoxazole 
• 914482-18-1 5-[2-(4-chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-4-yl)-ethyl]-3-methyl-4-nitroisoxazole 
• 914482-19-2 5-[2-(4-chlorophenyl)-2-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-ethyl]-3-methyl-4-nitroisoxazole 
• 1242340-72-2 C₂₇H₂₁ClN₆O₇ 

Relevant academic research and scientific papers

A fast, highly efficient and green protocol for Michael addition of active methylene compounds to styrylisoxazoles using task-specific basic ionic liquid [bmIm]OH as catalyst and green solvent

A fast, highly efficient and green protocol for the Michael addition of active methylene compounds to styrylisoxazoles at room temperature has been investigated using task-specific basic ionic liquid, 3-butyl-1-methyl imidazolium hydroxide, [bmIm]OH, as a

Multi-component synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N- oxides

A three component one-pot protocol was investigated for the synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N-oxides from commercially available materials.

Multicomponent synthesis of 3-heteroarylpropionic acids

(Chemical Equation Presented) A four component one-pot procedure (4-MC) was developed to assemble 3-heteroarylpropionic acids from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chr

Multicomponent synthesis of spiroisoxazolines

A three-component one-pot procedure (3-MCR) was developed to assemble the spiroisoxazoline nucleus from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chromatography.

Michael additions on isoxazole derivatives under solvent-free conditions

Knoevenagel condensation of 3,5-dimethyl-4-nitro-isoxazole 1 with aromatic aldehydes in solid state in the presence of piperidine gives 3-methyl-4-nitro-5-styryl-isoxazoles 2 in excellent yields within few minutes. Michael addition of active methylene com

Ethylene-diheterocycles: Part I - Synthesis of 5--3-methyl-4-nitroisoxazoles

Michael addition of acetylacetone to 3-methyl-4-nitro-5-styrylisoxazoles (I) in triethylamine leads to 3--2,4-pentanediones (II).The pentanediones (II) undergo cyclisation with hydroxylamine to give 5-ω