79514-33-3

Upstream product

• 5856-62-2 (S)-2-aminobutan-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 112934-17-5 N-(2-Biphenyl-4-yl-2-oxo-ethyl)-N-((S)-1-hydroxymethyl-propyl)-4-methyl-benzenesulfonamide 
• 112934-14-2 N-((S)-1-Hydroxymethyl-propyl)-4-methyl-N-(2-oxo-2-phenyl-ethyl)-benzenesulfonamide 
• 112934-16-4 N-[2-(4-Chloro-phenyl)-2-oxo-ethyl]-N-((S)-1-hydroxymethyl-propyl)-4-methyl-benzenesulfonamide 
• 1296866-34-6 (S)-N-allyl-N-(1-hydroxybutan-2-yl)-4-methylbenzenesulfonamide 
• 1207368-87-3 (S)-3-ethyl-4-tosylmorpholine 
• 334686-31-6 (-)-(2S,4S)-2-[(1S,3R)-1,3-dimethyl-2-methylenecyclohexyl]-4-ethyl-3-[(4-methylphenyl)sulfonyl]-1,3-oxazolidine 
• 334686-30-5 (+)-(2R,6R)-2-{(2S,4S)-4-ethyl-3-[(4-methylphenyl)sulfonyl]-1,3-oxazolidin-2-yl}-2,6-dimethylcyclohexan-1-one 
• 334686-29-2 (-)-(2R)-2-{(2S,4S)-4-ethyl-3-[(4-methylphenyl)sulfonyl]-1,3-oxazolidin-2-yl}-2-methylcyclohexan-1-one 
• 112934-15-3 N-((S)-1-Hydroxymethyl-propyl)-4-methyl-N-(2-oxo-2-p-tolyl-ethyl)-benzenesulfonamide 

Relevant academic research and scientific papers

Enantio- and Regioselective Palladium(II)-Catalyzed Dioxygenation of (Aza-)Alkenols

An oxidative Pd-catalyzed intra-intermolecular dioxygenation of (aza-)alkenols has been reported, with total regioselectivity. To study the stereoselectivity, different chiral ligands as well as different hypervalent-iodine compounds have been compared. I

N-7 SUBSTITUTED PURINE AND PYRAZOLOPYRIMINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE

The present invention relates to compounds of Formula I: wherein R1, R2, R3, A1, A2, A3, A4, Y1 and Y2 and D have the meaning described herein. The present invention also relates to pharmaceutical compositions comprising such compounds and therapeutic uses thereof.

First enantioselective total synthesis of both (+)- and (-)-metachromin A

The antineoplastic agent (-)-metachromin A (1) from Hippospongia metachromia has been synthesized in enantiomerically pure form in 13% overall yield. A general convergent synthetic strategy for different metachromins using a 2-alkyloxy-3-sulfonyl-l,3-oxazolidine as a chiral dithienium equivalent is presented.

New isoxazolidine-based chiral auxiliaries for asymmetric syntheses

New chiral auxiliaries based on the bicyclic-isoxazolidine skeleton, 3-oxa-2,7-diazabicylo[3,3,0]octane derivatives, were synthesized in 60-80% overall yields from amino acids. Asymmetric alkylation and boron aldol reaction using the auxiliaries proceeded with high selectivities. 'Carboxylic amide' has been used for the asymmetric boron-mediated aldol reaction for the first time.

Diastereoselective formation of 2-aryl-3-arenesulfonyl 4-ethyl-1,3-oxazolidines: An X-ray crystallographic and 1H NMR study

N-Arylsulfonamides of (R)- and (S)-2-amino-1-butanol, on condensation with aromatic aldehydes produced diastereomerically pure 2-aryl-3-arenesulfonyl 4-ethyl-1,3-oxazolidines. The absolute configurations of one enantiomeric pair have been determined from