79517-20-7

Upstream product

• 56782-26-4 (+/-)-sceletium alkaloid A₄ 
• 79477-39-7 {2-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-ethyl}-carbamic acid ethyl ester 
• 35135-35-4 (+/-)-sceletium alkaloid A₄ 
• 159898-43-8 Trifluoro-methanesulfonic acid 6-[2-(benzyl-methyl-amino)-ethyl]-6-(3,4-dimethoxy-phenyl)-5,6-dihydro-quinolin-7-yl ester 
• 776-99-8 3,4-dimethoxyphenylacetone 
• 159898-41-6 5-(Benzyl-methyl-amino)-3-(3,4-dimethoxy-phenyl)-pentan-2-one 
• 79477-44-4 6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinoline-6-carbonitrile 
• 79477-43-3 4-Allyloxyimino-1-(3,4-dimethoxy-phenyl)-cyclohexanecarbonitrile 
• 593-51-1 methylamine hydrochloride 
• 93414-08-5 (+/-)-mesembrine oxime O-allyl ether 
• 79477-48-8 3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide 
• 79477-47-7 3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid ethyl ester 
• 79477-45-5 6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinoline-6-carbaldehyde 
• 159898-42-7 5-(Benzyl-methyl-amino)-3-(2-bromo-pyridin-3-ylmethyl)-3-(3,4-dimethoxy-phenyl)-pentan-2-one 

Downstream Products

• 79517-21-8 (+/-)-N-formyltortuosamine 
• 93527-79-8 (+/-)-N-acetyltortuosamine 

Relevant academic research and scientific papers

Total synthesis of Sceletium alkaloids (±)-joubertinamine, (±)-epijoubertinamine, (±)-tortuosamine and formal synthesis of (±)-mesembrine, (±)-N-formyltortuosamine

An efficient collective formal/total synthesis of Sceletium alkaloids and their seco-congeners has been reported. The bicyclic core of (±)-mesembrine, (±)-tortuosamine, and (±)-N-formyltortuosamine with all required functionalities including the character

A short synthesis of (+)-tortuosamine

A four-step synthesis of (±)-tortuosamine (1) is described. The key ring closure was an intramolecular S(RN)1 reaction between a ketone enolate and a 2-halopyridine.

SYNTHESIS OF ALKALOIDS, (+/-)-SCELETIUM ALKALOID A4 AND (+/-)-N-ACETYLTORTUOSAMINE

Synthesis of alkaloids, (+/-)-Sceletium alkaloid A4 and (+/-)-N-acetyltortuosamine, was accomplished by application of a new method for constructing cycloalkenopyridines by thermal rearrangement of oxime O-allyl ethers.

Sceletium Alkaloids. Structures of Five News Bases from Sceletium namaquense

The structures of five alkaloids are reported.These include N-acetyltortuosamine (6), the dihydropyridone base (5) related to Sceletium alkaloid A4 (3), and three new alkaloids with the joubertiamine (2) skeleton represented by 4-(3,4-dimethoxy

SYNTHESIS OF ALKALOIDS, TORTUOSAMINE, N-FORMYLTORTUOSAMINE, AND RELATED COMPOUND

Synthesis of alkaloids, tortuosamine, N-formyltortuosamine, and related compound, was accomplished by application of a new method constructing cycloalkenopyridines by thermal rearrangement of oxime O-allyl ethers as a key step