795274-44-1

Usage

Uses

Used in Pharmaceutical Industry:
1-BROMO-3,5-BIS(TERT-BUTYLTHIO)BENZENE is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block for the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
1-BROMO-3,5-BIS(TERT-BUTYLTHIO)BENZENE is also utilized in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties allow for the creation of effective and targeted agrochemicals that can protect crops and enhance agricultural productivity.
As a Research Chemical:
In addition to its industrial applications, 1-BROMO-3,5-BIS(TERT-BUTYLTHIO)BENZENE serves as a research chemical, enabling scientists to explore its properties and potential applications in various fields, including materials science, organic synthesis, and medicinal chemistry.

InChI:InChI=1/C14H21BrS2/c1-13(2,3)16-11-7-10(15)8-12(9-11)17-14(4,5)6/h7-9H,1-6H3

Upstream product

• 461-96-1 3,5-difluorobromobenzene 
• 29364-29-2 sodium tert-butyl thiolate 
• 626-39-1 1,3,5-trisbromobenzene 

Relevant academic research and scientific papers

Discovery of practical production processes for arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides): Beginning of a new era of "super-trifluoromethyl" arene chemistry and its industry

Various arylsulfur pentafluorides, ArSF5, have long been desired in both academic and industrial areas, and ArSF5 compounds have attracted considerable interest in many areas such as medicines, agrochemicals, and other new materials, since the highly stable SF5 group is considered a "super-trifluoromethyl group" due to its significantly higher electronegativity and lipophilicity. This article describes the first practical method for the production of various arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides), from the corresponding diaryl disulfides or aryl thiols. The method consists of two steps: (Step 1) treatment of a diaryl disulfide or an aryl thiol with chlorine in the presence of an alkali metal fluoride, and (step 2) treatment of the resulting arylsulfur chlorotetrafluoride with a fluoride source, such as ZnF2, HF, and Sb(III/V) fluorides. The intermediate arylsulfur chlorotetrafluorides were isolated by distillation or recrystallization and characterized. The aspects of these new reactions are revealed and reaction mechanisms are discussed. As the method offers considerable improvement over previous methods in cost, yield, practicality, applicability, and large-scale production, the new processes described here can be employed as the first practical methods for the economical production of various arylsulfur pentafluorides and their higher homologues, which could then open up a new era of "super-trifluoromethyl" arene chemistry and its applications in many areas.

Bromine catalyzed conversion of S-tert-butyl groups into versatile and, for self-assembly processes accessible, acetyl-protected thiols

The facile and efficient conversion of a tert-butyl protecting group to an acetyl protecting group for thiols by catalytic amounts of bromine in acetyl chloride and the presence of acetic acid has been developed. The fairly mild reaction conditions are of