795281-89-9

Upstream product

• 286-20-4 cyclohexane-1,2-epoxide 
• 177948-70-8 (3R)-N(H)-3-(benzyloxy)pyrrolidine 
• 177947-67-0 (3R)-N-(tert-butyloxycarbonyl)-3-(benzyloxy)pyrrolidine 
• 900513-90-8 (1S,2S)-2-[(3R)-3-benzyloxy-1-pyrrolidinyl]cyclohexanol 

Downstream Products

• 867152-05-4 (1R,2R)/(1S,2S)-1-[(3R)-benzyloxypyrrolidinyl]-2-chlorocyclohexane 
• 900513-90-8 (1S,2S)-2-[(3R)-3-benzyloxy-1-pyrrolidinyl]cyclohexanol 

Relevant academic research and scientific papers

A fang chanfu law compound and its preparation method, pharmaceutical composition and use thereof

The invention relates to a new compound for conversion of auricular fibrillation, as shown in the general formula i in the specification (n in the formula is equal to 0 to 4), or pharmaceutically acceptable salt thereof. The invention also provides a novel compound used as a preventive medicine or therapeutic drug for atrial fibrillation, a preparation method and a pharmaceutical composition containing the compound.

PRODUCTION METHOD OF OPTICALLY ACTIVE CYCLOHEXANE ETHER COMPOUNDS

The present invention relates to an industrial synthetic method of an optically active cyclohexane ether compound (IIIa) or a salt thereof, which is useful as a pharmaceutical agent, and an intermediate useful for the production method of the present invention. The production method of the present invention is as shown below: wherein each symbol is as defined in the specification. According to the production method of the present invention, efficient and stable supply of an optically active cyclohexane ether compound (IIIa) in a high yield at a lower cost can be afforded. Therefore, an optically active cyclohexane ether compound (IIIa) extremely useful as a pharmaceutical agent can be provided by an industrially highly advantageous method.

MERGED ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF

Merged compounds of ion channel modulating compounds, including, for example, merged compounds of the ion channel modulating compound of the following formula: (I) are described herein, as well as methods of making and using such merged compounds and pharmaceutical compositions containing such merged compounds.