795308-12-2

Upstream product

• 795308-11-1 (2R/S,1'S)-1'-{[(tert-butyldiphenylsilyl)oxy]methyl}-6'-(1,3-dioxolan-2-yl)-4'-methyl-2',4'-hexadien-1'-yl 2-[(4-methoxybenzyl)oxy]-5-hexenoate 

Downstream Products

• 795308-17-7 methyl (1R,2S,3S,4R)-3,4-bis(acetyloxy)-2-[3'-(1,3-dioxolan-2-yl)-1'-methyl-1'-propen-1'-yl]-1-[(4-methoxybenzyl)oxy]cyclohexanecarboxylate 
• 795308-15-5 (1'R,3S,4S,5R,3aS,7aR) 3-[2'-(1,3-dioxolan-2-yl)-1'-iodoethyl]-4,5-dihydroxy-7a-[(4-methoxybenzyl)oxy]-3-methylhexahydro-2-benzofuran-1(3H)-one 
• 795308-18-8 methyl (1R,2S,3S,4R)-2-[3'-(1,3-dioxolan-2-yl)-1'-methyl-1'-propen-1'-yl]-3,4-dihydroxy-1-[(4-methoxybenzyl)oxy]cyclohexanecarboxylate 
• 795308-19-9 methyl (1R,2S,3S,4R)-3,4-bis(acetyloxy)-2-[3'-(1,3-dithiolan-2-yl)-1'-methyl-1'-propen-1'-yl]-1-hydroxycyclohexanecarboxylate 
• 795308-14-4 (1'R,3S,3aS,7aR)-3-[2'-(1,3-dioxolan-2-yl)-1'-iodoethyl]-7a-[(4-methoxybenzyl)oxy]-3-methyl-3a,6,7,7a-tetrahydro-2-benzofuran-1(3H)-one 
• 795308-24-6 methyl (1R,2R)-2-[3'-(1,3-dioxolan-2-yl)-1'-methyl-1'-propen-1'-yl]-1-[(4-methoxybenzyl)oxy]-3-cyclohexene-1-carboxylate 

Relevant academic research and scientific papers

A stereoselective formal synthesis of (-)-fumagillol

A novel formal synthesis of fumagillol, a direct precursor of the antiangiogenic sesquiterpene fumagillin, is described. The main features of the synthesis are a stereoselective Claisen-Ireland rearrangement, a ring-closing metathesis, a chemo- and stereo