79531-20-7Relevant academic research and scientific papers
Synthesis and stereochemical assignment of exo- and endo-7-methyl-7-azabicyclo[2.2.1]heptan-2-ol
Ramanaiah,Zhu, Naiju,Klein-Stevens, Cheryl,Trudell, Mark L.
, p. 1439 - 1441 (1999)
(formula presented) The syntheses of both the exo and endo stereoisomers of 7-methyl-7-azabicyclo[2.2.1]heptan-2-ol were achieved in straightforward fashion. Alternatively, the intramolecular cyclization of syn-4-N-methylaminocyclohexane 1,2-epoxide was f
Synthesis and bronchodilator activity of endo-2-(2-cyclopentyl-2-hydroxy-2-phenyl)acetoxy-7-methyl-7-azabicyclo-[2. 2.1]heptane methobromide, a potent and long-acting anticholinergic agent
Pfister,Wymann,Weissberg,Strossberg
, p. 208 - 210 (1985)
The synthesis of the α-cyclopentylmandelate ester of quaternized endo-7-methyl-7-azabicyclo[2.2.1]heptan-2-ol (4, RS-11635) is described. The key step of this synthesis consists of the intramolecular trans-diaxial epoxide opening of 4-(N-methylamino)-1,2-
