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Uridine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5,6-dihydro-5'-O-[(4-methoxyphenyl)diphenylmethyl]- is a complex organic compound derived from uridine, a nucleoside found in RNA. This specific derivative features a silyl protecting group at the 2' position and a bulky aryl protecting group at the 5' position. The silyl group, (1,1-dimethylethyl)dimethylsilyl, is used to protect the hydroxyl group, while the aryl group, (4-methoxyphenyl)diphenylmethyl, provides steric hindrance and additional stability. This chemical is significant in the field of nucleoside chemistry, particularly for research involving the synthesis and modification of nucleic acid components, and it may have applications in the development of new drugs and therapeutics.

79536-96-2

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79536-96-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 79536-96-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,5,3 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 79536-96:
(7*7)+(6*9)+(5*5)+(4*3)+(3*6)+(2*9)+(1*6)=182
182 % 10 = 2
So 79536-96-2 is a valid CAS Registry Number.

79536-96-2Downstream Products

79536-96-2Relevant academic research and scientific papers

Nucleosides, XXXVII. - Synthesis and Properties of 2'-O- and 3'-O-(tert-Butyldimethylsilyl)-5'-O-(4-methoxytrityl)- and 2',3'-Bis(O-tert-butyldimethylsilyl)ribonucleosides - Starting Materials for Oligoribonucleotide Syntheses

Flockerzi, Dieter,Silber, Gunter,Charubala, Ramamurthy,Schlosser, Wilhelm,Varma, Rajendra Singh,et al.

, p. 1568 - 1585 (2007/10/02)

The synthesis of aminoacylated 5'-O-(4-methoxytrityl)ribonucleosides of adenosine (1), guanosine (9), cytidine (31), uridine (17), and 5,6-dihydrouridine (23) have been optimized and these compounds (4, 12, 33, 18 and 24) silylated by tert-butyldimethylsilyl chloride.The corresponding 2'- and 3'-mono-O- as well as 2',3'-bis-O-(tert-butyldimethylsilyl) derivatives have been isolated by combination of chromatographical methods and fractional crystallization procedures in preparative scale.The characterization of the newly synthesized compounds was achieved by UV and 13C-NMR spectra.

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