79538-29-7

Basic information

• Product Name: 2,4,6-TRIFLUOROBENZOYL CHLORIDE
• Synonyms: TIMTEC-BB SBB005827;2,4,6-TRIFLUOROBENZOYL CHLORIDE;Benzoyl chloride, 2,4,6-trifluoro- (9CI);2,4,6-Trifluorobenzoyl chloride 98%;2,4,6-Trifluorobenzoylchloride98%;2,4,6-Trifluorobenzoyl chloride, 98% 1GR;2,4,6-Trifluorobenzoyl Chloride 98% by GC
• CAS NO: 79538-29-7
• Molecular Formula: C₇H₂ClF₃O
• Molecular Weight: 194.54
• Product Categories: ACIDHALIDE;Miscellaneous;Fluorine series;Pharm intermediate
• Mol File: 79538-29-7.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 167-168°C
• Flash Point: 167-168°C
• Appearance: colorless liquid.
• Density: 1.484
• Refractive Index: 1.4825-1.4845
• Water Solubility: hydrolysis in water
• Sensitive: Lachrymatory
• BRN: 1958563
• CAS DataBase Reference: 2,4,6-TRIFLUOROBENZOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIFLUOROBENZOYL CHLORIDE(79538-29-7)
• EPA Substance Registry System: 2,4,6-TRIFLUOROBENZOYL CHLORIDE(79538-29-7)

Safety Data

• Hazard Codes: C,T
• Statements: 34-25
• Safety Statements: 45-36/37/39-26
• RIDADR: 3265
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 79538-29-7(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to yellow liquid

InChI:InChI:1S/C7H2ClF3O/c8-7(12)6-4(10)1-3(9)2-5(6)11/h1-2H

Upstream product

• 28314-80-9 2,4,6-trifluorobenzoic acid 

Downstream Products

• 1193354-54-9 C₁₇H₁₂F₃N₃O₅S 
• 1401964-42-8 4,4′-dimethoxybenzhydryl 2,4,6-trifluorobenzoate 
• 1401963-05-0 4-methoxybenzhydryl 2,4,6-trifluorobenzoate 
• 1401963-04-9 4-phenoxybenzhydryl 2,4,6-trifluorobenzoate 
• 1401963-07-2 4-methoxy-4′-phenoxybenzhydryl 2,4,6-trifluorobenzoate 
• 1401963-06-1 4-methoxy-4′-methylbenzhydryl 2,4,6-trifluorobenzoate 
• 439239-90-4 Lasmiditan 
• 790669-79-3 4-[6-(2,4,6-trifluorobenzoylamino)pyridin-2-yloxy]piperidine-1-carboxylic acid tert-butyl ester 
• 850083-62-4 N-(6-aminopyridin-2-yl)-2,4,6-trifluorobenzamide 
• 193018-36-9 4-[(4-Bromo-3-methoxymethoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-amino]-2,6-difluoro-benzoic acid ethyl ester 
• 1025892-41-4 4-Azido-2,6-difluoro-benzoic acid ethyl ester 
• 191469-36-0 ethyl 2,6-difluoro-4-aminobenzoate 

Relevant articles and documents

PROCESSES AND INTERMEDIATE FOR THE LARGE-SCALE PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE HEMISUCCINATE, AND PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE ACE

The embodiments of present invention provide processes and an intermediate for the large-scale preparation of 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate, and formulations and product forms made by these processe

PROCESS FOR PREPARATION OF LASMIDITAN

The present invention relates to a process for the preparation of lasmiditan, a compound of formula I, or pharmaceutically acceptable salts thereof, the process comprising reacting a compound of formula IV with morpholine to obtain a compound of formula II, reacting the of formula III with a compound of formula IIA to obtain lasmiditan or salt thereof.

COMBINATION THERAPY WITH 2,3-DIHYDRO-ISOINDOLE-1-ONE COMPOUNDS AND METHODS FOR TREATING PATIENTS WITH VARIOUS MUTATIONS

The present disclosure comprises a method for administering 2,3-dihydro-isoindole-1-one compound or a pharmaceutically acceptable salt, ester, solvate and/or prodrug thereof, alone or in combination with an anticancer agent, for the treatment of hematolog