79544-98-2

Upstream product

• 2065-66-9 methyl-triphenylphosphonium iodide 
• 594-19-4 tert.-butyl lithium 
• 79544-52-8 2-fluoro-1-triphenylmethylimidazole 

Downstream Products

• 83628-26-6 4-(2-cyanovinyl)-2-fluoro-1-triphenylmethyl imidazole 
• 464924-56-9 (E)-3-(2-fluoro-1-trityl-1H-imidazol-4-yl)-acrylic acid ethyl ester 
• 464924-58-1 (Z)-3-(2-fluoro-1-trityl-1H-imidazol-4-yl)-acrylic acid methyl ester 

Relevant academic research and scientific papers

Cephalosporin derivatives

A cephalosporin derivative of the formula: STR1 in which R0 is a hydrogen atom or a methyl radical, R1 is any one of the C-3 substituents from antibacterially-active cephalosporins known in the art; R2 is any one of the C-4 substituents from antibacterially-active cephalosporins known in the art; R3 is a hydrogen atom or a 1-6C alkoxy or 1-6C alkylthio radical; X1 is a sulphur or oxygen atom, a CH2 radical or a radical of the formula NR7 in which R7 is a hydrogen atom, a 1-6C alkyl, formyl or benzyl radical; X2 is a nitrogen atom or a radical of the formula N≈ -R7 ; R4 and R7, and R5 and R6 are a variety of substituents which are described in the specification; and the pharmaceutically-acceptable acid- or base-addition salts thereof. Pharmaceutical compositions, manufacturing processes and intermediates are also described.

Cephalosporin derivatives

A compound of the formula I: STR1 in which R1 is any C-3 substituent from antibacterially-active cephalosporins; R2 is any C-4 substituent from antibacterially-active cephalosporins; R3 is H, hydroxy, amino, 1-6C alkyl, 1-