79546-83-1

Basic information

• Product Name: butyl methyl propanedioate
• CAS NO: 79546-83-1
• Molecular Formula: C₈H₁₄O₄
• Molecular Weight: 174.1944
• Mol File: 79546-83-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 218.4°C at 760 mmHg
• Flash Point: 99.5°C
• Density: 1.039g/cm³
• Vapor Pressure: 0.126mmHg at 25°C
• Refractive Index: 1.422
• CAS DataBase Reference: butyl methyl propanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: butyl methyl propanedioate(79546-83-1)
• EPA Substance Registry System: butyl methyl propanedioate(79546-83-1)

Safety Data

• Hazardous Substances Data: 79546-83-1(Hazardous Substances Data)

Upstream product

• 16695-14-0 Malonic acid monomethyl ester 
• 592-34-7 carbonochloridic acid, butyl ester 
• 123-86-4 acetic acid butyl ester 
• 79546-79-5 methyl 3-butoxy-3-diethylamino-3-fluoro-3-propanoate 
• 37517-81-0 3-chloro-3-oxopropanoic acid methyl ester 
• 71-36-3 butan-1-ol 
• 186581-53-3 diazomethane 
• 5917-45-3 3-butoxy-3-oxopropanoic acid 

Relevant articles and documents

Total synthesis of (-)-austalide B. A generic solution to elaboration of the Pyran/p-Cresol/Butenolide triad

The toxic meroterpenoid (-)-austalide B has been prepared in its natural form by chemical modification of the readily available optically active enedione 11. Following stereocontrolled Robinson annulation to give 13 and fully regiocontrolled gem-dimethyla

FLUORINATED 3-DIETHYLAMINOPROPENOATES AND THEIR REACTIONS

The reaction of diethylamine with methyl trifluoropropenoate (I), methyl 2-chloro-3,3-difluoropropenoate (II), methyl 3,3-difluoropropenoate (III) and methyl 3-chloro-2,3-difluoropropenoate (IV) affords halogenated 3-diethylaminopropenoates V-VII via the vinylic substitution of fluorine or chlorine atoms.When hydrolyzed the latter give methyl N,N-diethylcarbamoylacetates X-XII.On addition of 1-butanol and 2,2,3,3-tetrafluoropropanol to aminopropenoates V-VII fluorinated 3-alkoxy-3-diethylaminopropenoates XIII-XVI were prepared which when hydrolyzed eliminate thediethylamino group under formation of alkyl methylpropanedioates XX to XXIII.Heating of aminoethers XIII-XVI at 150 deg C gives 1-fluorobutane or 1,1,2,2,3-pentafluoropropane, respectively.These fluoro derivatives are also formed on heating of the mentioned alcohols with 3-diethylaminopropenoates V-VII.During the thermal decomposition of methyl 2-chloro-3-diethylamino-3-fluoro-3-(2,2,3,3-tetrafluoropropoxy)propanoate (XV) 3-chloro-1,1,2,2-tetrafluoropropane was formed as a by-product.The substitution of the hydroxyl group with fluorine is discussed from the point of view of preparative application.