79574-70-2Relevant academic research and scientific papers
A facile synthesis of 2,3-disubstituted furo[2,3-b]pyridines
Beutner, Gregory L.,Kuethe, Jeffrey T.,Yasuda, Nobuyoshi
supporting information; experimental part, p. 781 - 784 (2009/05/11)
In a three-step sequence starting from readily available starting materials, 2,3-carbon disubstituted furo[2,3-b]pyridines can be accessed in good yields and purity. Furo[2,3-b]pyridines bearing ester, amide and ketone groups at the 2-position can be prepared with a variety of aryl and alkyl groups at the 3-position.
5-Membered heterocyclic compound
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Page/Page column 40, (2009/07/03)
The present invention provides 5-membered heterocycle compounds represented by the following general formula (I): The present compounds have a superior acid secretion inhibitory effect, and shows an antiulcer activity and the like.
NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
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Page/Page column 25-26, (2008/12/06)
Compounds of Formula I: (I), are HIV reverse transcriptase inhibitors, wherein Q, R2, R3, R6, T1, T2, and T3 are defined herein. The compounds of Formula I, and the pharmaceutically accepta
HIV reverse transcriptase inhibitors
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Page/Page column 52-53, (2010/11/25)
Compounds having the structure: are HIV reverse transcriptase inhibitors, wherein A, X, Y, Z, R1 and R2 are defined herein. The compounds and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
METALLATION REGIOSELECTIVE EN SERIE PYRIDINIQUE: SYNTHESE ORIGINALE D'AMINO-2-AROYL 3-PYRIDINES
Guengoer, Timur,Marsais, Francis,Queguiner, Guy
, p. 139 - 150 (2007/10/02)
Lithium diisopropylamide reacts with 2-fluoropyridine at low temperature: regioselectivity is excellent and metallation occurs without side reactions such as nucleophilic attack. 2-Fluoro-3-lithiopyridine is formed and with aldehydes it gives the correspo
