79575-79-4Relevant academic research and scientific papers
A NEW STRATEGY FOR THE ENANTIOSELECTIVE SYNTHESIS OF THE δ-LACTONE MOIETY OF COMPACTIN AND MEVINOLIN
Mico, Antonella De,Piancatelli, Giovanni,Cacurri, Stefania,Lappa, Sperandina
, p. 415 - 419 (2007/10/02)
A new strategy for the preparation of optically active lactone analogues of the inhibitors of hydroxy-methylglutaryl-coenzyme A reductase is outlined.The lactone moiety has been elaborated by enzymatic resolution with porcine pancreas lipase of racemic 4-
