79576-58-2Relevant academic research and scientific papers
CHEMISTRY OF ENOLIC ETHERS. LI. SYNTHESIS AND INVESTIGATION OF THE STEREOCHEMISTRY OF THE ACETALS OF β,γ-UNSATURATED δ-HYDROXYALDEHYDES BY NMR SPECTROSCOPY
Raifel'd, Yu. E.,Kusikova, I. P.,Zil'berg, L. L.,Arshava, B. M.,Limanova, O. V.,Makin, S. M.
, p. 1425 - 1429 (2007/10/02)
A new accessible method is proposed for the synthesis of the acetals of ethynylacetaldehyde by the addition of bromine to the acetals of vinylacetaldehyde and subsequent dehydrobromination of the obtained 1,1-dialkoxy-3,4-dibromobutanes with sodium amide.The Iotich condensation of the ethynylacetaldehyde acetals with paraform and acetaldehyde was investigated.A stereoselective synthesis of the individual cis and trans isomers of β,γ-unsaturated δ-hydroxyaldehydes was realized from the obtained acetylenic alcohols.
