79588-25-3Relevant academic research and scientific papers
Synthesis and HPLC-separation of atropisomeric and central chiral 3-aryl-2-mercapto- and 3-aryl-2-alkylthio-4(3H)-quinazolinone derivatives on chiral stationary phases. Part I: Synthesis
Jira,Junghanel,Theiss,Kottke,Besch,Schopplich,Bunke,Leuthold,Beyrich
, p. 273 - 279 (2007/10/03)
In this paper the synthesis of atropisomeric and central chiral 3-aryl-2-mercapto-, 3-aryl-2-alkylthio-4(3 H)-quinazolinones with a chiral side chain are described. The spectroscopical data of the analytes and the HPLC-parameters on RP-phases are presented.
Synthesis of Benzimidazoquinazolines - Mechanism of Thiophosgene Heterocyclisation
Rastogi, Rashmi,Sharma, Satyavan
, p. 579 - 582 (2007/10/02)
A number of benzimidazoquinazolines (5-9) have been synthesized starting from 2-(2'-aminophenyl)benzimidazole (3).Reaction of 2-aminoanthranilide (2) with thiophosgene has been carried out and the mechanism of thiophosgene heterocyclisation has been discussed.The compounds have been tested for their anthelmintic and antinmicrobial activities but none of them shows any noteworthy activity.
