79592-91-9 Usage
Uses
Used in Pharmaceutical Industry:
CRASSICAULINE A is used as a neurotoxin antagonist for its ability to bind and activate tetrodotoxin-sensitive Na+ channels, thereby prolonging the opening of the sodium-ion channel and suppressing conformational changes. This makes it a potential candidate for the development of drugs targeting neurological disorders and pain management.
Used in Chemical Research:
As a white solid with unique chemical properties, CRASSICAULINE A can be used in chemical research for studying the structure, properties, and reactions of natural compounds. It can also be used as a reference material for the development of new synthetic methods and techniques in organic chemistry.
Used in Quality Control and Analysis:
CRASSICAULINE A can be used as a reference compound in quality control and analysis of natural products, ensuring the purity and authenticity of the compounds being studied or used in various applications. Its unique chemical properties make it a valuable tool for the development of analytical methods and techniques in the field of natural product chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 79592-91-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,5,9 and 2 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 79592-91:
(7*7)+(6*9)+(5*5)+(4*9)+(3*2)+(2*9)+(1*1)=189
189 % 10 = 9
So 79592-91-9 is a valid CAS Registry Number.
InChI:InChI=1/C35H49NO10/c1-8-36-17-32(18-40-3)14-13-23(42-5)35-22-15-33(39)24(43-6)16-34(46-19(2)37,26(29(35)36)27(44-7)28(32)35)25(22)30(33)45-31(38)20-9-11-21(41-4)12-10-20/h9-12,22-30,39H,8,13-18H2,1-7H3
79592-91-9Relevant academic research and scientific papers
Yang, Jing-Hua,Li, Zi-Yan,Li, Liang,Wang, Yun-Song
, p. 345 - 348 (1999)
Three new diterpenoid alkaloids, liaconitine A (N-ethyl- 1α,6α,16β,18-tetramethoxy-13β-ol-2,3-dehydroaconitane-8-acetate-14- anisoylate), B (N-ethyl- 1α,6α, 16β,18-tetramethoxy- 13β-ol-2,3- dehydroaconitane-8,14-dianisoylate and C (N-ethyl- 1α,6α,16β,18- tetramethoxy-8-ethoxy-13β-ol-2,3-dehydroaconitane-14-anisoylate) have been isolated from the roots of Aconitum episcopale. The structures of the new compounds were established by spectroscopic methods and reduction of liaconitine A to the known alkaloid, crassicauline A.
DEOXYGENATION REACTIONS OF C19-DITERPENOID ALKALOIDS
Kulanthaivel, Palaniappan,Pelletier, S. William
, p. 4313 - 4320 (2007/10/02)
Efficient methods for deoxygenation of secondary and tertiary alcohols of some C19-diterpenoid alkaloids are presented.Delphisine (12) was converted to 1-deoxydelphisine (19) via either 1,2-pyrodelphisine (17) or phenyl thionocarbonate 20.The following alkaloids were deoxygenated via their thiocarbonylimidazolyl derivatives: 14-acetyldelcosine (13) to 14-acetyl-1-deoxydelcosine (22); alkaline hydrolysis of 22 gave 1-deoxydelcosine (23); aconitine (24) to 3-deoxyaconitine (27); yunaconitine (25) to crassicauline A (28).Deoxygenation of 14-acetyldictyocarpine (30) via the chloro-derivate 31 gave 14-acetyl-10-deoxydictiocarpine (34).Reduction of 31 with LiAlH4 gave the unusual elimination product 32.An improved partial synthesis of hypaconitine (35) from aconitine (24) is also presented.
