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10-Hydroxyimipramine is a chemical compound derived from imipramine, a tricyclic antidepressant. It is formed as a major metabolite of imipramine in the human body, and it exhibits pharmacological activity. 10-Hydroxyimipramine has been found to possess antidepressant properties, although it is generally considered to be less potent than its parent compound. The chemical structure of 10-Hydroxyimipramine consists of a dibenzazepine core with a hydroxyl group at the 10th position, which differentiates it from imipramine. Its role in the therapeutic effects of imipramine is still a subject of research, as it is believed to contribute to the overall efficacy of the drug.

796-28-1

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796-28-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 796-28-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,9 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 796-28:
(5*7)+(4*9)+(3*6)+(2*2)+(1*8)=101
101 % 10 = 1
So 796-28-1 is a valid CAS Registry Number.
InChI:InChI=1/C19H24N2O/c1-20(2)12-7-13-21-17-10-5-3-8-15(17)14-19(22)16-9-4-6-11-18(16)21/h3-6,8-11,19,22H,7,12-14H2,1-2H3

796-28-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 11-[3-(dimethylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-5-ol

1.2 Other means of identification

Product number -
Other names Hydroxyimipramine,10

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:796-28-1 SDS

796-28-1Upstream product

796-28-1Downstream Products

796-28-1Relevant academic research and scientific papers

Metabolism of imipramine by microorganisms

Hufford,Capiton,Clark,Baker

, p. 151 - 155 (2007/10/02)

The microbial metabolism of imipramine was studied using selected fungal organisms. The major microbial metabolites were isolated, and their structures were established by spectroscopic analyses (particularly 13C-NMR) and by comparison with authentic samples. The microbial metabolites identified included 2-hydroxyimipramine, 10-hydroxyimipramine, iminodibenzyl, imipramine-N-oxide, and desipramine; these metabolites also have been found in mammalian metabolism studies.

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