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4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride, also known as (?)-Cis-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride, is a specific enantiomer of the drug nafadotride. It is a chemical compound that functions as a selective antagonist for the dopamine receptor D3. 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride has potential applications in the treatment of various psychiatric and neurological disorders, such as drug addiction, depression, and Parkinson's disease. The hydrochloride salt form is commonly used for pharmaceutical purposes, and it is crucial to handle it with care due to its potential effects on the central nervous system and its toxicity if ingested or inhaled.

79617-99-5

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79617-99-5 Usage

Uses

Used in Pharmaceutical Industry:
4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride is used as a pharmaceutical agent for the treatment of various psychiatric and neurological disorders. Its application is based on its ability to act as a selective antagonist for the dopamine receptor D3, which plays a significant role in the regulation of mood, motivation, and motor control.
Used in Drug Addiction Treatment:
In the field of addiction medicine, 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride is used as a therapeutic agent to help manage drug addiction. Its mechanism of action involves blocking the dopamine receptor D3, which may help reduce cravings and relapse in individuals struggling with addiction.
Used in Depression Treatment:
4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride is utilized as an antidepressant, targeting the dopamine receptor D3 to potentially alleviate symptoms of depression. The modulation of this receptor may contribute to improvements in mood and emotional well-being.
Used in Parkinson's Disease Management:
In neurology, 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride is employed in the management of Parkinson's disease. Its use as a D3 receptor antagonist may help in controlling motor symptoms and potentially slowing the progression of the disease by influencing the dopaminergic system.

Check Digit Verification of cas no

The CAS Registry Mumber 79617-99-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,6,1 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 79617-99:
(7*7)+(6*9)+(5*6)+(4*1)+(3*7)+(2*9)+(1*9)=185
185 % 10 = 5
So 79617-99-5 is a valid CAS Registry Number.

79617-99-5 Well-known Company Product Price

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  • (1612528)  Sertraline hydrochloride Related Compound A  United States Pharmacopeia (USP) Reference Standard

  • 79617-99-5

  • 1612528-25MG

  • 14,929.20CNY

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79617-99-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(3,4-dichlorophenyl)-N-methyl-3,4-dihydro-2H-naphthalen-1-imine,hydrochloride

1.2 Other means of identification

Product number -
Other names (1S*,4R*)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:79617-99-5 SDS

79617-99-5Downstream Products

79617-99-5Relevant academic research and scientific papers

COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, AND METHODS OF TREATMENT OF MENOPAUSE AND MOOD, ANXIETY, AND COGNITIVE DISORDERS

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Page/Page column 20; 23, (2008/06/13)

One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders.

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