79643-73-5Relevant academic research and scientific papers
Generation and reactivity of 1,2-cyclohexadiene under mild reaction conditions
Quintana, Lago,Pena, Diego,Perez, Dolores,Guitian, Enrique
experimental part, p. 5519 - 5524 (2010/02/28)
An improved method to generate 1,2-cyclohexadienes by fluoride-induced ss-elimination of 6-(trimethylsilyl)cyclohexenyl triflates is presented. This method allows the generation of these highly strained cyclic alienes in good yields and under mild reactio
A regiodefined synthesis of α-trimethylsilyl ketones catalyzed by rhodium(I) hydride complex
Sato, Susumu,Matsuda, Isamu,Izumi, Yusuke
, p. 71 - 88 (2007/10/02)
Regiodefined synthesis of α-trimethylsilyl ketones is attained by one of three different routes: isomerization of β-trimethylsilyl allyl alcohols (route A), isomerization of β'-trimethylsilyl allyl alcohols (route B), and dehydrogenation of β-trimethylsil
Synthesis of Trimethylsilyloxy and Hydroxy Compounds from Carbanions and Bis(trimethylsilyl)peroxide.
Camici, Lucia,Dembech, Pasquale,Ricci, Alfredo,Seconi, Giancarlo,Taddei, Maurizio
, p. 4197 - 4206 (2007/10/02)
The reactions of bis(trimethylsilyl)peroxide with alkyl, vinyl, alkynyl, aromatic and heteroaromatic anions are described.Depending on the reaction conditions, the trimethylsilyloxy derivatives can be obtained alone or together with the corresponding trimethylsilyl derivatives, which is sometimes the major product.Enolates, generated using magnesium diisopropylamide give the corresponding hydroxycarbonyl compounds in good yields.An attempt to rationalise the above results is given, emphasising the wide use of bis(trimethylsilyl)peroxide in organic synthesis as an electrophilic hydroxylation reagent.
AN OXIDATIVE ROUTE TO α-TRIMETHYLSILYL KETONES BY MEANS OF RHODIUM CATALYZED DEHYDROGENATION OF β-TRIMETHYLSILYL ALCOHOLS
Sato, Susumu,Matsuda, Isamu,Izumi, Yusuke
, p. 4229 - 4230 (2007/10/02)
The transfer hydrogenation of β-trimethylsilyl alcohols catalyzed by HRh(PPh3)4 has been successfully applied to the efficient synthesis of α-trimethylsilyl ketones.
SYNTHESE VON CYCLISCHEN α-TRIMETHYLSILYLKETONEN
Beisswenger, Harald,Hanack, Michael
, p. 403 - 404 (2007/10/02)
Cyclic α-trimethylsilylketones 10 ar synthesized from cyclic vynilmethylsilanes via the epoxides 8, and the alcohols 9.
Some Epoxide Ring-opening Reactions of αβ-Epoxysilanes
Davis, Anthony P.,Hughes, Gwyneth J.,Lowndes, Peter R.,Robbins, Catherine M.,Thomas, Elizabeth J.,Whitham, Gordon H.
, p. 1934 - 1941 (2007/10/02)
Epoxide ring-opening of 1,2-epoxy-1-trimethylsilylcyclohexane (3) has given a range of the 2-substituted 2-trimethylsilylcyclohexanols (4; X = H, OH, OMe, OCH2CH=CH2, Br, I, SCN) in which attack by nucleophile has occured at the carbon α to silicon.The products (4) have been transformed into a number of functionalised silanes, including the silyl-episulphide (9).Other epoxides which have been less extensively studied are the conformationally biased epoxysilanes (10) and (11), the eight-membered ring epoxysilanes (17) and (21) and the two stereoisomeric 2,3-epoxy-3-trimethylsilylpentanes (26) and (29).Epoxide ring-opening adducts were obtained after treatment with H+-MeOH in all cases except for compound (17), where the bicyclic alcohol (18) was formed by a transannular reaction.
