796869-82-4Relevant articles and documents
Synthesis of (-)-tabtoxinine-β-lactam, the phytotoxin of tobacco wildfire disease
Kiyota, Hiromasa,Takai, Takafumi,Shimasaki, Yasuharu,Saitoh, Masatoshi,Nakayama, Osamu,Takada, Tomoko,Kuwahara, Shigefumi
, p. 2471 - 2480 (2007)
Synthesis of (-)-tabtoxinine-β-lactam and its (3R)-isomer, the cause of tobacco wildfire disease, was achieved from L-serine using a zinc-mediated coupling reaction, Sharpless asymmetric dihydroxylation and lactamization of β-mesyloxy benzylhydroxamate amide as the key steps. Georg Thieme Verlag Stuttgart.