796874-61-8Relevant articles and documents
Lewis acid mediated regioselective ring opening of benzylglycidol with dibenzyl phosphate: Short and attractive synthesis of dihydroxyacetone phosphate
Meyer, Odile,Ponaire, Sarah,Rohmer, Michel,Grosdemange-Billiard, Catherine
, p. 4347 - 4350 (2007/10/03)
(Chemical Equation Presented) A novel, mild, and efficient method was described to introduce a dibenzyl phosphate by ring opening of benzylglycidol mediated by Lewis acids. This methodology was used as a key step for synthesizing the dihydroxyacetone phosphate (DHAP) in only three steps with an overall yield of 74% from the commercially available racemic benzylglycidol.
Short and efficient synthesis of a stock material of dihydroxyacetone phosphate from glycidol
Meyer, Odile,Rohmer, Michel,Grosdemange-Billiard, Catherine
, p. 7921 - 7923 (2007/10/03)
As enzymatic syntheses are expensive for a large-scale preparation of DHAP, a precursor leading to DHAP was synthesized in three steps starting from (±) glycidol; the stable benzylated stock material afforded by hydrogenolysis DHAP in high purity, which may be used directly without purification in enzymatic aldol synthesis.
