796883-66-4Relevant academic research and scientific papers
Synthesis and characterization of novel 5-monocarbohydrate-10,20- bis -aryl-porphyrins
Figueira, Flávio,Louren?o, Leandro M. O.,Neves, Maria G. P. M. S.,Cavaleiro, José A. S.,Tomé, Jo?o P. C.
, p. 330 - 339 (2019/09/17)
The synthesis of derivatives bearing glucose or galactose units linked by an acrylate spacer to one free meso position of a bis-aryl-porphyrin macrocycle was developed and characterized by standard spectroscopic techniques. The new mono-substituted gluco- and galacto-porphyrin derivatives 5-8 present an alternative to the widespread tetra-aryl porphyrin functionalization. Singlet oxygen studies showed a comparable singlet oxygen production with TPP. Furthermore, the less bulky architectures here synthesized present an opportunity to enhance the PDT and PDI capabilities of glycoporphyrins with a simple synthetic modification at one of the meso positions.
The dithianyl group as a synthon in porphyrin chemistry: Condensation reactions and preparation of formylporphyrins under basic conditions
Senge, Mathias O.,Matscher, Sabine S.,Wiehe, Arno,Dahms, Katja,Kelling, Andrea
, p. 13634 - 13635 (2007/10/03)
Vilsmeier formylation is one of the most widely used substitution reactions for the functionalization of porphyrins. However, its utility is limited by the electrophilic/acidic reaction conditions, deactivation of the aromatic system and regiochemical pro
