796883-94-8Relevant academic research and scientific papers
Unified total syntheses of the inositol polyphosphates: D-I-3,5,6P 3, D-I-3,4,5P3, D-I-3,4,6P3, and D-I-3,4,5,6P4 via catalytic enantioselective and site-selective phosphorylation
Morgan, Adam J.,Komiya, Shio,Xu, Yingju,Miller, Scott J.
, p. 6923 - 6931 (2007/10/03)
Synthetic routes to various inositol polyphosphates have been discovered utilizing catalytic enantioselective and site-selective phosphorylation reactions. The syntheses described herein exploit a common intermediate to gain efficient access to eight unique inositol polyphosphates.
Streamlined synthesis of phosphatidylinositol (PI), PI3P, PI3, 5P 2, and deoxygenated analogues as potential biological probes
Xu, Yingju,Sculimbrene, Bianca R.,Miller, Scott J.
, p. 4919 - 4928 (2007/10/03)
Highly direct total syntheses of phosphatidylinositol (PI), phosphatidylinositol-3-phosphate (PI3P), phosphatidylinositol-3,5-bisphosphate (PI3,5P2), and a range of deoxygenated versions are reported. Each synthesis is carried out to deliver th
Asymmetric syntheses of phosphatidylinositol-3-phosphates with saturated and unsaturated side chains through catalytic asymmetric phosphorylation
Sculimbrene, Bianca R.,Xu, Yingju,Miller, Scott J.
, p. 13182 - 13183 (2007/10/03)
Highly direct asymmetric syntheses of phosphatidylinositol-3-phosphate (PI3P) in each enantiomerically pure form have been achieved. The key step involves catalytic asymmetric phosphorylation of meso-myo-inositol derivatives through desymmetrization. Prot
