79692-11-8

Upstream product

• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 94051-93-1 1-phenyl-1,2,3,4-tetrahydronaphthalen-1-ol 

Downstream Products

• 503131-00-8 (1R,2S)-1-phenyl-2-hydroxy-1,2,3,4-tetrahydronaphthalene 
• 14578-75-7 1-phenyl-3,4-dihydronaphthalen-2(1H)-one 

Relevant academic research and scientific papers

Dynamic kinetic resolution-asymmetric transfer hydrogenation of 1-aryl-substituted cyclic ketones

A range of 1-aryl-2-tetranols, and 1-phenyl-2-indanol, have been generated in high yield and enantiomeric excess from the corresponding racemic ketones, via a dynamic kinetic resolution-transfer hydrogenation process, using Ru(II)-TsDPEN in formic acid/triethylamine (5:2). This provides a potential entry to an asymmetric total synthesis of benzazepines such as Sch 39166.

A concise synthesis of 1-substituted-2-tetralones by selective diol dehydration leading to ketone transposition

Dehydration of 1-substituted-1,2-tetralindiols with zinc iodide afforded the corresponding 2-tetralones in excellent yields. This procedure was found to be superior to the more conventional BF3-catalyzed rearrangement of 1-substituted-1,2-epoxytetralins. (C) 2000 Elsevier Science Ltd.