796966-76-2

Upstream product

• 5390-04-5 pent-1-yn-5-ol 
• 195314-47-7 2-bromo-4-methoxy-1-(methoxymethoxy)-benzene 
• 150-76-5 4-methoxy-phenol 

Downstream Products

• 796966-73-9 1-allyloxy-2-(5-iodopent-1-ynyl)-4-methoxybenzene 
• 796966-65-9 5-(2-allyloxy-5-methoxyphenyl)pent-4-yn-1-ol 
• 796966-77-3 2-(5-iodopent-1-ynyl)-4-methoxy-1-methoxymethoxybenzene 
• 796966-64-8 2-(5-hydroxypent-4-ynyl)-4-methoxyphenol 

Relevant academic research and scientific papers

Palladium-catalyzed couplings to nucleophilic heteroarenes: The total synthesis of (-)-frondosin B

The total synthesis of (-)-frondosin B, the enantiomer of naturally-occuring (+)-frondosin B, is described, wherein a palladium-catalyzed cyclization is used to establish the tetracyclic ring system of the natural product. Graphical Abstract.