79756-11-9Relevant articles and documents
A New Approach to Phosphoserine and Phosphothreonine Synthons Suitable for the Stepwise Synthesis of Phosphopeptides.
Mora, N.,Lacombe, J. M.,Pavia, A. A.
, p. 2461 - 2464 (2007/10/02)
Several phosphoserine and phosphothreonine synthons suitable for the stepwise synthesis of phosphopeptides have been prepared.Treatment of methylthiomethyl (MTM) esters of either benzyloxycarbonyl (Z), tert-butyloxycarbonyl (Boc) and allyloxycarbonyl (Alloc) serine and/or threonine with phosphochloridate in pyridine, followed by MgBr2 cleavage of MTM in diethylether, afforded the title compounds in excellent yields.