79756-19-7

Basic information

• Product Name: (2S,4S,5S)-2-amino-3,4-dimethyl-5-phenyl-1,3,2-thiazaphospholidin-2-one
• CAS NO: 79756-19-7
• Molecular Weight: 242.282
• Mol File: 79756-19-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4S,5S)-2-amino-3,4-dimethyl-5-phenyl-1,3,2-thiazaphospholidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S,5S)-2-amino-3,4-dimethyl-5-phenyl-1,3,2-thiazaphospholidin-2-one(79756-19-7)
• EPA Substance Registry System: (2S,4S,5S)-2-amino-3,4-dimethyl-5-phenyl-1,3,2-thiazaphospholidin-2-one(79756-19-7)

Safety Data

• Hazardous Substances Data: 79756-19-7(Hazardous Substances Data)

Upstream product

• 65960-90-9 (2S,4S,5S)-3,4-Dimethyl-5-phenyl-2-thioxo-2λ⁵-[1,3,2]oxazaphospholidin-2-ylamine 
• 65960-90-9 (2R)-3,4c-dimethyl-5c-phenyl-2-thioxo-2λ⁵-[1,3,2]oxazaphospholidin-2r-ylamine 

Relevant articles and documents

1,3,2-Thiazaphospholidin-2-ones Derived From Ephedrine. Preparation and Stereochemistry of Ring-opening Reactions

1,3,2-thiazaphospholidin-2-ones are prepared by rearrangement of the corresponding 1,3,2-oxazaphospholidine-2-thiones.In both the phosphono- and phosphoro-series treatment with alkoxide results in P-N bond cleavage with inversion of configuration, while treatment with Grignard reagents results in P-S bond cleavage with retention of configuration.The products are consistent with a mechanism which involves initial nucleophilic attack opposite endocyclic nitrogen.