797762-15-3Relevant academic research and scientific papers
Process and Methods for the Preparation of Gabapentin and Its Intermediates
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Page/Page column 3-7, (2009/03/07)
The invention provides a process for preparing gabapentin and its intermediates. The process generally involves treating gabapentin lactam with an aqueous solution of hydrobromic acid to yield gabapentin hydrobromide salt as an intermediate, which can be isolated by filtration. The gabapentin hydrobromide salt can then be hydrolyzed with a base, such as an organic amine, to yield gabapentin that can be isolated by filtration.
PROCESS AND METHODS FOR THE PREPARATION OF GABAPENTIN AND ITS INTERMEDIATES
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Page/Page column title page; 3; 6-17; 1/6, (2008/06/13)
The invention provides a process for preparing gabapentin and its intermediates. The process generally involves treating gabapentin lactam with an aqueous solution of hydrobromic acid to yield gabapentin hydrobromide salt as an intermediate, which can be isolated by filtration. The gabapentin hydrobromide salt can then be hydrolyzed with a base, such as an organic amine, to yield gabapentin that can be isolated by filtration.
