797762-48-2Relevant academic research and scientific papers
Pd/Cu-Catalyzed aerobic oxidative aromatic C-H bond activation/N-dealkylative carbonylation towards the synthesis of phenanthridinones
Shi, Renyi,Niu, Huiying,Lu, Lijun,Lei, Aiwen
supporting information, p. 1908 - 1911 (2017/02/10)
It is important to achieve diverse functionalization of tertiary anilines due to their importance in biological molecules, pharmaceutical, functional materials, and ligands. A straightforward Pd/Cu-catalyzed oxidative C-H bond activation/N-dealkylative carbonylation of tertiary [1,1′-biphenyl]-2-anilines towards the synthesis of various biologically important phenanthridin-6(5H)-ones has been developed. A wide range of functional groups are well tolerated in this transformation. Moreover, O2 is utilized as the terminal oxidant to promote the oxidative carbonylation process.
Pd-catalyzed dehydrogenative annulation approach for the efficient synthesis of phenanthridinones
Li, Xinyao,Pan, Jun,Song, Song,Jiao, Ning
, p. 5384 - 5389 (2016/08/02)
A novel Pd-catalyzed intermolecular dehydrogenative annulation of aryl iodides and aryl carbamic chlorides for the efficient synthesis of phenanthridinone derivatives was developed. Simple aryl iodides and carbamic chlorides readily made from various anil
Samarium(II)-mediated spirocyclization by intramolecular aryl radical addition onto an aromatic ring
Iwasaki, Hiroki,Eguchi, Toru,Tsutsui, Nozomi,Ohno, Hiroaki,Tanaka, Tetsuaki
supporting information; experimental part, p. 7145 - 7152 (2009/05/07)
(Chemical Equation Presented) Samarium(II)-mediated spirocyclization by intramolecular addition of aryl radicals onto an aromatic ring was achieved by the reaction of N-(2-iodophenyl)-N-alkylbenzamides with SmI2 in the presence of HMPA, yielding spirocyclic indolin-2-one derivatives. The ether congeners afford spirocyclic benzofuran derivatives in moderate yields by aryl radical addition onto a benzene ring without having an electron-withdrawing group. The reaction with other aryl groups such as naphthalene and indole rings is also described.
The first samarium(II)-mediated aryl radical cyclisation onto an aromatic ring
Ohno, Hiroaki,Iwasaki, Hiroki,Eguchi, Toru,Tanaka, Tetsuaki
, p. 2228 - 2229 (2007/10/03)
Intramolecular arylation of aryl radicals was mediated by SmI 2/HMPA in the presence of i-PrOH to give spirocycles and/or reduced cine-cyclised products, while the reaction in the absence of i-PrOH gave the rearomatised fused rings.
