797784-94-2Relevant academic research and scientific papers
A cross-metathesis route to functionalized α-methyl α-substituted amino acids
Storcken, Roy P. M.,Panella, Lavinia,Van Delft, Floris L.,Kaptein, Bernard,Broxterman, Quirinus B.,Schoemaker, Hans E.,Rutjes, Floris P. J. T.
, p. 161 - 164 (2008/02/03)
A chemoenzymatic approach to the synthesis of functionalized α-methyl α-substituted amino acids is detailed. This involves amidasemediated enzymatic resolution of α-methyl α-substituted side-chain ω-unsaturated amino acids followed by functionalization via cross-metathesis.
