79794-88-0Relevant academic research and scientific papers
Polymeric malondialdehyde dianils - A novel type of electrically conducting polymers
Gompper, Rudolf,Mueller, Thomas J. J.,Polborn, Kurt
, p. 2011 - 2018 (2007/10/03)
The reaction of vinamidinium salts with para-substituted aromatic diamines gives rise to polymeric 2-aryl malonaldehyde dianils in good yields. Polymeric cyanines can be obtained from tetramethoxypropane and a pentamethine cyanine, respectively, and para-substituted aromatic diamines. The degree of polymerisation Pn (n=10-40) was estimated by measuring the intrinsic viscosity η. The polymers show high electrical powder conductivities (σ=0.03-50 S cm-1) after doping with iodine or FeCl3.
New Pathwys Towards Long-Chain Substituted Dibenzotetraazaannulenes
Forget, S.,Veber, M.,Strzelecka, H.
, p. 263 - 276 (2007/10/02)
The synthesis of nickel complexes dibenzotetraazaannulenes bearing four, six or eight long paraffinic chains is described.Preliminary results concerning the mesomorphic properties of such systems show that those compounds exhibit a wide range hexagona
Analogues of platelet activating factor. 7. Bis-aryl amide and bis-aryl urea receptor antagonists of PAF
Wissner,Carroll,Johnson,Kerwar,Pickett,Schaub,Torley,Trova,Kohler
, p. 4779 - 4789 (2007/10/02)
A series of bis-aryl amide (13-57 and 66-81) and bis-aryl urea (58 and 85) antagonists of platelet-activating factor (PAF) was prepared that contain, separating the two aromatic rings, linear amide linkages of the form - (CH2)(n)CONH- (n = 0-2), -OCH2CONH-, and -(CH2)(n)NHCO- (n = 0-1), branched amide linkages of the form -(CH2)(n)N(COR)- (n = 1-3, R = CH3 or n-C3H7), and -N(COCH3)CH2-, and urea linkages of the form -NHCONH- and - CH2N(CONHCH3)-. These compounds were examined for their ability to inhibit PAF-induced platelet aggregation of rabbit platelets. These in vitro data were compared to similar data obtained for a number of known PAF antagonists. The compounds were evaluated in vivo, in the mouse, for their ability to prevent death induced by a lethal challenge of PAF. The relationships between the biological activity and the nature, lipophilicity, and position of substituents of the aromatic rings were studied. Best activity was observed for compounds having linkages of the type -CH2CONH-, -CH2N(COR)-, and - CH2NHCO-. Many of these compounds inhibit PAF-induced platelet aggregation with IC50's under 1 μM.
4-Hydroxy-3-pyrrolin-2-ones and treatment of circulatory disorders therewith
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, (2008/06/13)
The present invention relates to a compound of the formula: STR1 wherein X is sulfur or optionally substituted imino group; Y is a bond, oxygen, phenylene, phenyleneoxy, or oxyphenyleneoxy; R1 is hydrogen or optionally substituted hydrocarbon r
Hydroxybutenolide derivatives, production and use thereof
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, (2008/06/13)
The present invention relates to a compound of the formula: STR1 wherein Y is a chemical bond, oxygen atom, phenyleneoxy, or oxyphenyleneoxy; R1 is hydrogen or hydrocarbon residue; and R2 is hydrocarbon residue having two or more car
MESOGENIC DITHIOLATES: NEW DISK LIKE Π-ACCEPTORS
Veber, M.,Fugnitto, R.,Strzelecka, H.
, p. 221 - 228 (2007/10/02)
Starting from p-hydroxyphenylacetic acid we have been able to synthesize mesogenic dithiolates of transition metals with long chain substituents.Introduction of n-alkoxy side chains reduces the electronic affinity of this system, nevertheless those compou
