79807-86-6

Basic information

• Product Name: Benzene, 1-(2-bromoethyl)-4-phenoxy-
• CAS NO: 79807-86-6
• Molecular Formula: C14H13BrO
• Molecular Weight: 277.161
• Mol File: 79807-86-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(2-bromoethyl)-4-phenoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2-bromoethyl)-4-phenoxy-(79807-86-6)
• EPA Substance Registry System: Benzene, 1-(2-bromoethyl)-4-phenoxy-(79807-86-6)

Safety Data

• Hazardous Substances Data: 79807-86-6(Hazardous Substances Data)

Upstream product

• 52446-51-2 2-(4-phenyloxyphenyl)ethyl alcohol 
• 67-36-7 4-phenoxy benzaldehyde 
• 4973-29-9 4-phenoxystyrene 
• 6328-74-1 4-phenoxyphenylacetic acid 
• 101-55-3 4-Bromodiphenyl ether 

Downstream Products

• 4973-29-9 4-phenoxystyrene 
• 79808-03-0 3-<(4-phenoxyphenethyl)oxy>-1-nitrobenzene 
• 79807-87-7 2-({3-[2-(4-Phenoxy-phenyl)-ethoxy]-phenylamino}-methylene)-malonic acid diethyl ester 
• 79807-88-8 ethyl 7-<(4-phenoxyphenethyl)oxy>-4-hydroxyquinoline-3-carboxylate 
• 79808-15-4 3-<(4-phenoxyphenethyl)oxy>aniline 
• 1433543-94-2 N-hydroxy-2-(2-(4-phenoxyphenyl)ethylsulfonamido)acetamide 
• 1433545-97-1 C₁₇H₁₉NO₅S 
• 344596-80-1 Na⁽¹⁺⁾*C₁₄H₁₃O₄S^(1-) 

Relevant articles and documents

NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF

The invention provides compounds for inhibiting glucosylceramidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.

Discovery of a new class of potent MMP inhibitors by structure-based optimization of the arylsulfonamide scaffold

A new class of potent matrix metalloproteinase (MMP) inhibitors designed by structure-based optimization of the well-known arylsulfonamide scaffold is presented. Molecules show an ethylene linker connecting the sulfonamide group with the P1' aromatic portion and a D-proline residue bearing the zinc-binding group. The affinity improvement provided by these modifications led us to discover a nanomolar MMP inhibitor bearing a carboxylate moiety as zinc-binding group, which might be a promising lead molecule. Notably, a significant selectivity for MMP-8, MMP-12, and MMP-13 was observed with respect to MMP-1 and MMP-7.