79822-55-2

Upstream product

• 18305-80-1 hydroxy-1, benzyl-1, methoxy-6 tetrahydro-1,2,3,4 naphtalene 
• 68-12-2 N,N-dimethyl-formamide 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 97232-01-4 2-(diethoxymethyl)-6-methoxy-1-tetralone 
• 108530-22-9 1-Benzyl-2-diethoxymethyl-6-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ol 

Downstream Products

• 69847-25-2 3-methoxybenzanthracene 

Relevant academic research and scientific papers

Synthesis of α,β-Unsaturated Aldehydes by 1,3-Carbonyl Transposition through One Carbon Homologation. Part 2

The easily accessible 2-(diethoxymethyl)-6-methoxy-1-tetralone (1) on condensation with methylmagnesium iodide and benzylmagnesium chloride followed by treatment with BF3*Et2O affords 6-methoxy-1-methyl-3,4-dihydro-2-naphthaldehyde (2) and 1-benzyl-6-methoxy-3,4-dihydro-2-naphthaldehyde (3), respectively.The carbinols derived from the reaction of 2-(diethoxymethyl)-1-indanones (4a-4c) with methyllithium undergo smooth transformations to the respective 3-methyl-1H-indene-2-aldehydes (5a-5c). endo-2-(p-Methoxyphenyl)-5-methylbicyclooctan-6-en-7-aldehyde (14) has been prepared from endo-2-(p-methoxyphenyl)-5-methylbicyclooctan-6-one (12) through the respective diethoxymethyl derivative (12) by sodium borohydride reduction followed by acid-catalysed rearrangement of the resulting diacetal carbinol.

Applications of the Vilsmeier Reaction. 13. Vilsmeier Approach to Polycyclic Aromatic Hydrocarbons

The synthesis of three typical polycyclic hydrocarbons (PAH) has been described, wherein the Vilsmeier reaction plays a major role.Vilsmeier reaction of the tetralol 1 gives the dihydronaphthaldehyde 2 which on cyclodehydration gives the dihydroarene 3.It