79822-86-9Relevant academic research and scientific papers
INFRARED AND ULTRAVIOLET SPECTRA OF SECONDARY 2-THIOPHENECARBOTHIOAMIDES. A CONFORMATIONAL STUDY.
Jagodzinski, T.,Jagodzinska, E.,Dziembowska, T.,Szczodrowska, B.
, p. 449 - 458 (2007/10/02)
Analysis of the infrared and ultraviolet spectra gave evidence of non-planarity of secondary 2-thiophenecarbothioamides with predominance of the trans(Z)-s-trans conformation.Calculations by the CNDO/2 method are presented for the s-ciss-trans equilibr
Facile Conversions of Carboxylic Acids into Amides, Esters, and Thioesters Using 1,1'-Oxalyldiimidazole and 1,1'-Oxalyldi(1,2,4-triazole)
Kitagawa, Tokujiro,Kuroda, Hiroko,Sasaki, Hideaki,Kawasaki, Koichi
, p. 4294 - 4301 (2007/10/02)
Aliphatic, aromatic, and heteroaromatic carboxylic acids react with 1,1'-oxalyldiimidazole (1) or 1,1'-oxalyldi(1,2,4-triazole) (2) in acetonitrile for 40 min at 40 degC to give the corresponding 1-acylazole intermediates (11), which promptly undergo aminolysis and alcoholysis to form amides (13) including dipeptides (14), esters (16), and thioesters (19).These findings show that both 1 and 2 can be utilized as condensing reagents for the synthesis of carboxylic acid derivatives.Keywords --- 1,1'-oxalyldiimidazole; 1,1'-oxalyldi(1,2,4-triazole); 1,1'-carbonyldiimidazole; 1-acylazole; condensing reagent; amidation; esterification; dipeptide; aminolysis; alcoholysis
