79841-40-0Relevant academic research and scientific papers
Ni(ii)-Catalyzed vinylic C-H functionalization of 2-acetamido-3-arylacrylates to access isotetronic acids
Das, Eshani,Mal, Dipakranjan,Roy, Avijit,Roy, Biswajit
supporting information, p. 3697 - 3706 (2020/06/03)
A ligand-free Ni(ii)-catalyzed cascade annulation reaction for the synthesis of 4-aryl-substituted isotetronic acids from 2-acetamido-3-arylacrylatesviavinylic C-H functionalization is reported. The reaction proceeds through heteroatom guided electrophilic insertion of nickel to the vinylic double bond followed by annulation with dibromomethane. This unconventional route features cascade steps, sole product formation, multiple functional group tolerance, low cost of catalysts and reagents, and readily available starting materials. Using this method, various aryl-substituted isotetronic acids have been synthesized which are biologically relevant. The annulation of 2-acetamido-3-arylacrylates has also been assessed with 1,2-dichloroethane, which resulted in the rearranged annulated products of 5-methyl substituted isotetronic acids.
Boron-catalyzed direct aldol reactions of pyruvic acids
Lee, Doris,Newman, Stephen G.,Taylor, Mark S.
supporting information; experimental part, p. 5486 - 5489 (2010/02/28)
"Chemical Equation Presented" Interactions between pyruvic acids and diphenylborinic acid form the basis of an efficient, direct, boron-catalyzed aldol reaction that takes place in water at room temperature with low catalyst loadings. Both boronic and bor
1,5-Hydride shift in products of Stevens 3,2-rearrangement of methyl(alkyl)(alkoxycarbonylmethyl)-(3-phenyl-2- propynyl)ammonium bromides
Ovsepyan,Babakhanyan,Manukyan,Kocharyan
, p. 1376 - 1382 (2007/10/03)
The products of the Stevens 3,2-rearrangement of ammonium salts containing methyl and other (ethyl, propyl, butyl) alkyl groups along with 3-phenylprop-2-ynyl, under the reaction conditions undergo, roughly by half, intramolecular hydride shift with inter
Intramolecular 1,5-hydride shift in products of stevens 3,2-rearrangement of ammonium salts containing 3-phenyl-2-propynyl group
Babakhanyan,Ovsepyan,Kocharyan,Panosyan
, p. 814 - 819 (2007/10/03)
In products of Stevens 3,2-rearrangement of ammonium salts containing alongside alkoxycarbonylmethyl also 3-phenyl-2-propynyl group an intramolecular 1,5-hydride shift is observed resulting in immonium salts which transform into aminoesters of enamine str
Phase Transfer Catalysed Double Carbonylation of Styrene Oxides
Alper, Howard,Arzoumanian, Henri,Petrignani, Jean-Francois,Saldana-Maldonado, Manuel
, p. 340 - 341 (2007/10/02)
A novel double carbonylation of styrene oxides occurs on treatment of the heterocycle with carbon monoxide, methyl iodide, NaOH (0.5 M), C6H6, Co2(CO)8 as the metal catalyst, and cetyltrimethylammonium bromide as the phase transfer agent.
Base Catalysed Rearrangements Involving Ylide Intermediates. Part 11. Rearrangements of 3-phenylprop-2-ynylammonium Ylides
Mageswaran, Sivapathasuntharam,Ollis, W. David,Southam, Dolores A.,Sutherland, Ian O.,Thebtaranonth, Yodhathai
, p. 1969 - 1980 (2007/10/02)
The propynylammonium salt (5) reacts with aqueous sodium hydroxide to give the allene (7) and a new ylide (11).The simultaneous formation of (7) and (11) suggests that the apparent sigmatropic rearrangement of the propynyl ylide (6) to the allene (7
